???? ????? ???? ??? ??? ???? ???? ???? ?? ?? ????? ??????, ??? ?? ????? ??.??? ??? ???? ? ??? ???? ???, ??? ?? ???? ??? ???? ?????.When sildenafil improves some markers of ailment in those with pulmonary arterial hypertension, it doesn't look to have an affect on the potential risk of death or significant Unwanted effects.[20]??, ??? ??? ???? ?????